Custom Antigens for today’s unmet needs & tomorrow’s innovation

Antigen and Protein Purification Experts

Logical Antigen specialises in the customised development of high-quality antigens and biologicals for research and manufacturing of diagnostic products. Antigens are a key component in the manufacture of in vitro diagnostic (IVD) test reagents, often used in controls to confirm test performance. However, unmet needs currently exist in relation to protein derived material availability, suitability and consistent performance. We aim to drive scientific and clinical innovation through agile and client-focused antigen manufacturing.

Our team of experts have decades of experience in protein purification and are ready to discuss customised options.

Antigens

Precision- engineered antigens, developed for your diagnostic success

Leveraging advanced biotechnology platforms tailored to complex biological requirements and the highest standards of quality, we can design, develop, and produce customised antigens tailored specifically to the needs of IVD manufacturers.

A tailored approach ensures antigens retain their functional and immunological relevance to achieve maximum performance in your applications. Starting with the end in mind, Logical Antigen focusses on quality controlled, reliable processes that deliver long term supply sustainability at large scale.

Antigen Manufacturing
Antigen HPLC columns

Our Capabilities

Our capabilities are based on refined extraction, isolation, and purification techniques from native biological sources, to preserve structural conformation, post-translational modifications, and biological activity. The expert team also offers recombinant antigen development services to support diverse project requirements and achieve superior performance through novel downstream purification protocols.

  • Custom antigen design
  • Native protein extraction and purification
  • Recombinant protein downstream purification
  • Pilot and commercial-scale production
  • Analytical characterisation and QC support

Partnering with Logical Antigen

 

Biospecimen Experts

Expertise in Antigen Design

With years of experience in protein purification our scientists bring deep technical knowledge to every project. We understand the critical role antigens play in assay performance and are skilled at designing antigens that optimise sensitivity, specificity, and stability.

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Rapid Prototyping & Scale-Up

With scientific precision, reliability and speed, the expert Logical Antigen team can complete antigen development in a matter of weeks – accelerating traditional timescales of years – enabling clients to move faster with their discovery, verification and product development.

We can rapidly scale up production, to meet growing demand without compromising on quality or delivery timelines.

matched sets

Biological Material Access

We can access a comprehensive range of raw materials, including serum, plasma, urine, tissue, whole blood, and seminal fluid, to create antigens that truly reflect native biological conditions. This ensures your assays achieve exceptional sensitivity and specificity across a range of diagnostic applications.

Customisation

Customisation to Fit Your Application

Every diagnostic platform has unique requirements. We work closely with you to customise antigens that are optimised for your assay format. From targeted protein extraction, pilot scale & large-scale purification that is in line with specific analyser purity requirement, we tailor every step to meet your needs.

Quality Assurance

Proven Quality and Consistency

Our custom antigens are developed under stringent quality control processes to ensure batch-to-batch consistency and reproducibility, crucial factors in regulated diagnostic environments.