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Antibodies

HAMA-Time! – How Human Anti-Mouse Antibodies (HAMA) can affect your immunoassay

What is HAMA? HAMA is an acronym for Human Anti-Mouse Antibodies. Some humans produce HAMA and have it present in their blood. Unfortunately for them, and the in vitro diagnostics industry, the presence of Human anti-mouse Antibodies (HAMA) in patient samples can lead to false positive and false negative results in immunoassays. Murine MC HAMA Why do some Humans produce HAMA? Some people work directly with mice while others might inadvertently encounter...

James Steggles
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Irregular Blood Group Antibodies – What Are They?

Irregular antibodies are antibodies found in the blood of transfusion donors that have the potential to cause hemolysis of the recipient blood. Screening using an indirect Coombs Test should be performed to ensure that the donor blood is compatible with the recipient. “Irregular Antibodies” refers to all antibodies, other than those detecting ABO blood group antigens, that can cause incompatibility in blood transfusions and between mother & child. The ABO Blood...

James Steggles
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