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The utility of SARS-CoV-2 IgA in COVID-19 testing

At the outset of the 2019 SARS-CoV-2 / COVID-19 epidemic, diagnostic immunoassay manufacturers focused on developing anti-SARS-CoV-2 IgM & IgG tests. While the epidemic has progressed to become a global pandemic, diagnostic test developers’ efforts have also evolved. Recently, we have noticed an increase in interest for patient material positive for Human anti-SARS-CoV-2 IgA. This article will take a look at the difference between the different immunoglobulin sub-classes and seek to...

James Steggles
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The time we saved a woodpecker during our lunch-break

Here at Logical Biological we care about reducing our environmental impact. We are lucky to work in a rural location and get to see lots of wildlife around our HQ at Discovery Park. A few days ago, we were able to put our environmentally conscious aims into practice when we saved a Green Woodpecker. We noticed the beautiful bird, caught upside down with its legs tangled in synthetic nesting material...

James Steggles
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SARS-CoV-2 – Beware Antibody Tests with <100% Specificity

We are in the midst of the most significant global pandemic since the 1918-19 Influenza pandemic, over 100 years ago. The 2020 pandemic has been caused by a Coronavirus, named SARS-CoV-2, which confers a severe respiratory illness (COVID-19) on a proportion of those infected. The virus is readily transmissible from human to human with many of those infected showing no or mild symptoms, meaning it is hard to know who...

James Steggles
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EPS Waste

As we move into 2020, one thing we'd like to do at Logical Biological is find a greener way of dealing with polystyrene box waste. The material has fantastic properties making it ideal for use in shipping biological reagents around the world. It is incredibly lightweight, a great insulator and it can withstand some knocking around, so it is no surprise that our industry uses so much of it. The...

James Steggles
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Chagas positive plasma added to range

Logical Biological has added Chagas antibody positive plasma to its range having received clearance from the UK government Health & Safety Executive to handle human biological material containing Trypanosoma cruzi, which is the causative agent of Chagas Disease. T. cruzi is a Hazard Group 3 pathogen according to “The Approved List of Biological Reagents”. Hazard Group 3 is defined as follows: “Can cause severe human disease and may be a serious hazard to employees; it may...

James Steggles
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Irregular Blood Group Antibodies – What Are They?

Irregular antibodies are antibodies found in the blood of transfusion donors that have the potential to cause hemolysis of the recipient blood. Screening using an indirect Coombs Test should be performed to ensure that the donor blood is compatible with the recipient. “Irregular Antibodies” refers to all antibodies, other than those detecting ABO blood group antigens, that can cause incompatibility in blood transfusions and between mother & child. The ABO Blood...

James Steggles
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