Toxoplasma IgM – not a smoking gun for acute infection
Toxoplasma gondii is a protozoan parasite present in a third of the world’s human population. People acquire this infection in three ways: i) inadequately cooked infected meat, particularly pork, ii) unwitting ingestion of oocysts passed in cat feces, which could, for example, occur whilst gardening, and iii) pregnant women passing the infection transplacentally to their unborn fetus – known as Congenital Toxoplasmosis. In most cases the infection is asymptomatic or...
Chagas positive plasma added to range
Logical Biological has added Chagas antibody positive plasma to its range having received clearance from the UK government Health & Safety Executive to handle human biological material containing Trypanosoma cruzi, which is the causative agent of Chagas Disease. T. cruzi is a Hazard Group 3 pathogen according to “The Approved List of Biological Reagents”. Hazard Group 3 is defined as follows: “Can cause severe human disease and may be a serious hazard to employees; it may...
Irregular Blood Group Antibodies – What Are They?
Irregular antibodies are antibodies found in the blood of transfusion donors that have the potential to cause hemolysis of the recipient blood. Screening using an indirect Coombs Test should be performed to ensure that the donor blood is compatible with the recipient. “Irregular Antibodies” refers to all antibodies, other than those detecting ABO blood group antigens, that can cause incompatibility in blood transfusions and between mother & child. The ABO Blood...
Fertility drugs & IVD fertility testing
All over the planet, women are getting pregnant, over 200 million of them each year. Most of these pregnancies are unintended1. This means two things: a lot of babies, and a lot of surprises. Despite this, some 8% of couples are unable to conceive within two years and are considered infertile. Risk factors for infertility include age, previous medical history (sexually-transmitted diseases, cancer treatment) and obesity. Fortunately, a wide-range of fertility treatments are now available, although sadly...
HIV – a challenging disease to diagnose
Human Immunodeficiency Virus (HIV) has a reputation for being difficult to treat, although advances in medicine have reached a level where those being treated can be expected to live almost to their full life span. However, as we shall see in this article, current HIV testing is not perfect and many challenges remain. There are multiple HIV viruses HIV is actually a small family of distinct viruses comprised of HIV1 and HIV2....
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